Bacterial infections are responsible for a wide spectrum of diseases in humans causing significant morbidity and mortality on a global scale. Bacteria can survive in two different forms: free-living planktonic form and biofilm form. Bacterial biofilms are densely packed communities of bacterial cells which are surrounded by a self-produced polymeric matrix. It is reported that over 80% of microbial infections including many chronic diseases in humans are associated with biofilm. Apart from causing havoc in the form of deadly diseases, biofilm bacteria can make medical implants malfunctional or non-functional. The infection caused by planktonic form of bacteria can be comparatively more easily cured by antibiotic treatment. However, the resistance of bacteria to antibiotics and other antimicrobial agents increase by nearly a thousand fold in the biofilm state.