While traditional vaccine modalities continue to play an important role, 87% of the respondents intend to focus on mRNA and the majority believe this modality will dominate the future vaccine landscape. Most manufacturers stated an intent to establish capabilities in novel vaccine platforms and indicated that both traditional and modern cell-based vaccines remain important given their proven regulatory record, high efficacy, and generally fewer side effects.

Given the protection offered by the SARS-CoV-2 mRNA vaccines and the accelerated development timelines, it’s no surprise that this modality has gained significant traction and interest across the biopharmaceutical industry. When comparing the development times of different modalities, nucleic acid-based vaccines have the fastest development time, and as an established platform technology, mRNA enables a tremendous amount of manufacturing flexibility and production speed.

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